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Nvidia Parabricks MambaSV
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NVIDIA
Nvidia Parabricks MambaSV

MambaSV is a somatic and germline structural variant (SV) caller for long-read sequencing using bidirectional Mamba2 state-space models.

LayerLabelCreated
sha256:a3ed95caeb02ffe68cdd9fd84406680ae93d633cb16422d00e8a7c22955b46d4USER
mambasv
10/01/2026 6:24 PM UTC
sha256:39e9a605e6b2111d0e59375811211c9836977d7d9c384238c2eca79715b87bc7RUN
RUN /bin/sh -c python - <<'PY' from pathlib import Path import importlib.metadata import subprocess expected = { 'GitPython': ('3.1.59', '3.1.60'), 'transformers': ('5.8.1', '5.17.0'), 'safetensors': ('0.7.0', '0.8.0'), 'tokenizers': ('0.22.2', '0.23.1'), } for package, (_, version) in expected.items(): assert importlib.metadata.version(package) == version, package notice = Path('/opt/mambasv/licenses/THIRD-PARTY.txt') content = notice.read_text() for package, (old, new) in expected.items(): content = content.replace(f'Package: {package}\nVersion: {old}', f'Package: {package}\nVersion: {new}') notice.write_text(content) packages = subprocess.check_output( ['python', '-m', 'pip', 'list', '--format=freeze'], text=True) Path('/opt/mambasv/licenses/PYTHON_PACKAGES.txt').write_text( '\n'.join(sorted(packages.splitlines())) + '\n') PY # buildkit
10/01/2026 6:24 PM UTC
sha256:1e059328c485c64e4f0ec924ad84eedea640219b7a4362621787564e473dc3e1RUN
python -m pip install --upgrade --no-index --find-links=/wheels --only-binary=:all: GitPython==3.1.60 transformers==5.17.0 safetensors==0.8.0 tokenizers==0.23.1 &&
  python -m pip check
10/01/2026 6:24 PM UTC
sha256:a3ed95caeb02ffe68cdd9fd84406680ae93d633cb16422d00e8a7c22955b46d4USER
root
10/01/2026 6:24 PM UTC
sha256:a3ed95caeb02ffe68cdd9fd84406680ae93d633cb16422d00e8a7c22955b46d4LABEL
com.nvidia.mambasv.somatic.normal-matches-fix=tuple-annotation
09/26/2026 11:29 PM UTC
sha256:8512c433251bad95fc3ddcf77aafd2d8302765d495e58223635d3edce5a1e438RUN
PYTHONPATH=/opt/mambasv MAMBASV_REQUIRE_COMPILED=1 python /tmp/test_somatic_normal_matches.py
09/26/2026 11:29 PM UTC
sha256:6afb37913fb6d9d3e1620c882bd9b84971e84a9213ad979bc2dae6b0b376ee57COPY
/opt/somatic-update/ /opt/mambasv/
09/26/2026 11:24 PM UTC
sha256:a3ed95caeb02ffe68cdd9fd84406680ae93d633cb16422d00e8a7c22955b46d4USER
mambasv
09/10/2026 4:55 PM UTC
sha256:756ea65ab15e7d0731e4c6ad8b5b7f09b8cb9adff6d80964e52f7142c43c14bcRUN
apt-get update &&
  DEBIAN_FRONTEND=noninteractive apt-get install -y --no-install-recommends --only-upgrade openssl=3.0.2-0ubuntu1.29 libssl3=3.0.2-0ubuntu1.29 &&
  rm -rf /var/lib/apt/lists/* /opt/conda/lib/python3.14/site-packages/msgpack /opt/conda/lib/python3.14/site-packages/msgpack-1.1.2.dist-info &&
  cp -a /mnt/patch/. / &&
  test "$(dpkg-query -W -f='${Version}' openssl)" = "3.0.2-0ubuntu1.29" &&
  test "$(dpkg-query -W -f='${Version}' libssl3)" = "3.0.2-0ubuntu1.29" &&
  /opt/conda/bin/openssl version | grep -q '^OpenSSL 3.6.4 ' &&
  python -c 'import msgpack, ssl; assert msgpack.__version__ == "1.2.1"; assert ssl.OPENSSL_VERSION.startswith("OpenSSL 3.6.4 ")' &&
  python -m pip check
09/10/2026 4:55 PM UTC
sha256:a3ed95caeb02ffe68cdd9fd84406680ae93d633cb16422d00e8a7c22955b46d4USER
root
09/10/2026 4:55 PM UTC
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