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Boltz-2
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Boltz-2

Boltz-2 NIM is a next-generation structural biology foundation model that shows strong performance for both structure and affinity prediction.

  • LayerLabelCreated
    sha256:a3ed95caeb02ffe68cdd9fd84406680ae93d633cb16422d00e8a7c22955b46d4ENTRYPOINT
    ["/bin/bash" "-c" "$SERVER_START_SCRIPT_PATH"]
    03/31/2026 8:15 AM UTC
    sha256:f3d02d4b1e4a8a1e928e368002e2fc94a90b7ac65a8bc78630f4e4980936e20eRUN
    RUN |3 TELEMETRY_MODE=0 TELEMETRY_ENDPOINT=0 PIP_INDEX_URL=https://urm.nvidia.com/artifactory/api/pypi/nv-shared-pypi/simple /bin/sh -c touch $SERVER_START_SCRIPT_PATH &&
      chmod a+rx $SERVER_START_SCRIPT_PATH &&
      cat > $SERVER_START_SCRIPT_PATH <<-EOF #!/usr/bin/env bash set -eu # SPDX-FileCopyrightText: Copyright (c) 2024 NVIDIA CORPORATION & AFFILIATES. All rights reserved. # SPDX-License-Identifier: LicenseRef-NvidiaProprietary echo "NIMTools: \$NIMTOOLS_VERSION" start_server EOF # buildkit
    03/31/2026 8:15 AM UTC
    sha256:a3ed95caeb02ffe68cdd9fd84406680ae93d633cb16422d00e8a7c22955b46d4ENV
    SERVER_START_SCRIPT_PATH=/opt/nim/start_server.sh
    03/31/2026 8:15 AM UTC
    sha256:aa672cf9dc383faff23584e7d439a82334d2aeac82c419ebe388b52c66d79c41COPY
    model_manifest.yaml /opt/nim/etc/default/model_manifest.yaml
    03/31/2026 8:15 AM UTC
    sha256:a3ed95caeb02ffe68cdd9fd84406680ae93d633cb16422d00e8a7c22955b46d4USER
    nvs:1000
    03/31/2026 8:15 AM UTC
    sha256:f3339d7dd4725d5480e0d0970b3a19987abba9c19854e8d07737663c8f049e80RUN
    TELEMETRY_MODE=0 TELEMETRY_ENDPOINT=0 PIP_INDEX_URL=https://urm.nvidia.com/artifactory/api/pypi/nv-shared-pypi/simple [ -d /etc/ld.so.conf.d ] ||
      mkdir -p /etc/ld.so.conf.d &&
      [ -f /etc/ld.so.conf.d/nvidia.conf ] ||
      touch /etc/ld.so.conf.d/nvidia.conf &&
      echo "/usr/local/nvidia/lib" >> /etc/ld.so.conf.d/nvidia.conf &&
      echo "/usr/local/nvidia/lib64" >> /etc/ld.so.conf.d/nvidia.conf &&
      echo "/usr/local/cuda/lib64" >> /etc/ld.so.conf.d/nvidia.conf &&
      if command -v ldconfig >/dev/null 2>&1; then ldconfig; fi &&
      /tmp/remove_packages.sh &&
      rm -f /tmp/remove_packages.sh
    03/31/2026 8:15 AM UTC
    sha256:6002b174aedb0b2307f8c9ea06674cee115b2b414f169315ead4ef00a978dbf7RUN
    TELEMETRY_MODE=0 TELEMETRY_ENDPOINT=0 PIP_INDEX_URL=https://urm.nvidia.com/artifactory/api/pypi/nv-shared-pypi/simple groupadd --gid 1000 --non-unique nvs &&
      useradd --create-home --shell /usr/sbin/nologin --uid 1000 --non-unique --gid 1000 nvs &&
      chown 1000.1000 $NIM_DIR_PATH
    03/31/2026 8:15 AM UTC
    sha256:8a78243d7cb380cd8c9016da329c425c0566a4c34d68a626210e819d9c034a9fCOPY
    ./LICENSE ./VERSION /opt/nim
    03/31/2026 8:15 AM UTC
    sha256:1c2308b444eff7b952576eaa745bfa5c14ec792d38f197ae3ad92c4be24acc4dCOPY
    ./data_models.py ./inference.py /opt/nim
    03/31/2026 8:15 AM UTC
    sha256:a3027cab412b564b11f6956097788448a050aa2b8c62659c320fa9ea636b3a4aRUN
    TELEMETRY_MODE=0 TELEMETRY_ENDPOINT=0 PIP_INDEX_URL=https://urm.nvidia.com/artifactory/api/pypi/nv-shared-pypi/simple rm -rf /usr/local/lib/python3.12/dist-packages/setuptools/_vendor/wheel* &&
      rm -rf /usr/lib/python3/dist-packages/setuptools/_vendor/wheel* &&
      rm -rf /usr/lib/python3/dist-packages/pkg_resources/_vendor/wheel*
    03/31/2026 8:15 AM UTC
    ...

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